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Recent Advances in the Use of Cell Penetrating Peptides

Gunnar Dietz, Göttingen

Start date: Mar 25, 2009 - End date: Mar 29, 2009

Over the last 15 years, many publications described the use of peptide sequences that have been dubbed cell penetrating peptides (CPP), Trojan horse peptides, protein transduction domains, or membrane-translocating sequences. These mostly positively charged domains bring attached cargo across biological membranes. One of the reasons for the interest in CPP is their potential as delivery tools to enhance the pharmacodynamics of drugs otherwise poorly bioavailable. In particular, the neuroscientist aiming to deliver a protein or other compounds into the brain for analytical or therapeutic reasons is faced with the challenge that few drugs cross the blood-brain barrier. CPP are valuable tools to overcome the plasma membrane or the blood-brain barrier in basic research, and in relevant models of neural disease, and will hopefully help to increase the precious few treatments or even cures for people with diseases of the brain and nervous system. In this symposium, the most acclaimed pioneers and world leaders of the field will give an update on recent developments using cell penetrating peptides.

Dead line for submiting abstracts: Jan 1, 2008

Contact information

Prof. Dr. med. Mathias Bähr
Neurologische Klinik
+49 (0) 551 39 6603
E-mail: mbaehr@gwdg.de

More information: http://www.neuro.uni-goettingen.de/nbc.php?sel=call_symposia

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