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• Leader sequence:

  A short, hydrophobic sequence at the N-terminal end of a protein. Its function is to transfer that protein across a membrane (such as the endoplasmic reticulum or cell membrane) by inserting itself into the membrane. After translocation, the leader sequence is cleaved from the remainder of the protein, leaving a fully soluble protein.

• Leukemia:

  Malignant diseases in which the bone marrow and other blood-forming organs produce increased numbers of leucocytes.

 

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